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KMID : 0359320100500010063
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Korean Journal of Veterinary Research
2010 Volume.50 No. 1 p.63 ~ p.69
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Application of thromboxane synthetase inhibitor (Ozagrel HCl) in feline infectious peritonitis
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Kim Tae-Sin
Lee Sun-Hee
Lim Soo-Jung
Song Kun-Ho
Park Hyung-Jin
Song Eun-Sik
Chung Dae-Wook
Kim Duck-Hwan
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Abstract
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A Persian chinchila (2 years old, intact female) and a Korean domestic shorthaired cat (3 months, intact male) were referred to the Veterinary Medical Teaching Hospital of Chungnam National University with tachypnea. The two cats were diagnosed as feline infectious peritonitis (FIP) by blood and blood chemical examination, radiographic examination, RT-PCR and electrophoresis analysis of pleural effusion. Thromboxane synthetase inhibitor (Ozagrel HCl, 5 mg/kg, twice a day) was administered to the Persian chinchila and Korean domestic shorthair for 13 days and 16 days, respectively. Pleural effusion disappeared after treatment with Ozagrel HCl. Further study is needed to establish a new application protocol of Ozagrel HCl for FIP cases.
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KEYWORD
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Feline infectious peritonitis, Ozagrel HCl, pleural effusion, thromboxane synthetase inhibitor
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